| Last Name | First Name | Pos | Org | Class | |
|---|---|---|---|---|---|
| Zych | Tony | P | CHN | AA | View |
| Zurcher | Chad | 2B | NYN | R+ | View |
| Zunino | Mike | C | SEA | Coll-A | View |
| Zumaya | Richard | P | A | View | |
| Zuloaga | Scott | P | HOU | A- | View |
| Zuanich | Mike | DH | COL | AA | View |
| Zrenda | Ryan | 2B | A- | View | |
| Zorrilla | Alexander | 2B | IntR | View | |
| Zorrilla | Janelfry | CF | SEA | IntR | View |
| Zornes | Adam | C | A+ | View | |
| Zocchi | P.J. | P | A+ | View | |
| Zobrist | Ben | 2B | TBA | MLB | View |
| Zizinia | Drew | P | A- | View | |
| Zito | Barry | P | SFN | MLB | View |
| Zinicola | Zech | P | BAL | AA | View |
| Zimmermann | Jordan | P | WAS | MLB | View |
| Zimmerman | Ryan | 3B | WAS | MLB | View |
| Zimmer | Kyle | P | HOU | A | View |
| Ziegler | Brad | P | ARI | MLB | View |
| Zevada | Oscar | 1B | Int | View | |
| Zeller | Joseph | P | KCA | A | View |
| Zeigler | Randall | P | SFN | A- | View |
| Zeid | Josh | P | HOU | AA | View |
| Zebroski | Thomas | 3B | R+ | View | |
| Zazueta | Amadeo | SS | TOR | Win | View |
| Zazueta | Vincent | SS | R+ | View | |
| Zazueta | Christian | CF | Int | View | |
| Zayas | Crysthian | LF | YUC | Int | View |
| Zawadzki | Lance | SS | TOR | AAA | View |
| Zawacki | Brett | P | R | View | |
| Zavala | Gabriel | P | A | View | |
| Zavada | Clay | P | AAA | View | |
| Zaun | Gregg | C | FA | MLB | View |
| Zarraga | Jonesy | CF | OAK | IntR | View |
| Zarraga | Shawn | C | MIL | A+ | View |
| Zarate | Robert | P | HAN | R | View |
| Zaragoza | Ernesto | P | R+ | View | |
| Zapenas | Brad | 2B | KCA | A- | View |
| Zapata | Oliver | CF | KCA | A- | View |
| Zapata | Nelfi | C | NYN | A- | View |
| Zapata | Pedro | LF | NYN | Win | View |
| Zaneski | Zach | C | TEX | A+ | View |
| Zambrano | Alfredo | SS | IntR | View | |
| Zambrano | Eliezer | C | SFN | AA | View |
| Zambrano | Carlos | P | MLB | View | |
| Zamarripa | James | CF | SEA | R | View |
| Zaleski | Matt | P | AAA | View | |
| Zagurski | Mike | P | PIT | MLB | View |
| Zagone | Richard | P | BAL | AAA | View |
| Zachary | Matt | P | IND | View |